As far as I know most or all RTV are (I guess latex based could be called RTV) silicone based. GE does make some of the best silicone on the market. My bro for a while installed PVC roofing and GE is all they used for sealing. But that was over 20years ago so I dont know how it stacks up now.
For building engines I used either GE or black RTV to seal water passages and valley covers with no failures also, but did have trouble sealing head studs that were open to the water jacket on my 406. I think locktite is what I finally got to work for those.
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