Let me see if I can clarify or not.
For a given flow rate, you will have a pressure drop from the inlet to the outlet of the block. The pressure drop is relative to where you place the measuring points. It doesn't matter where in the loop you place the block, you will get the same pressure drop across those two points. You get a pressure difference across the inlet and outlet of a pump. Without it you get no flow.
Or like an individual cell in a battery. It doesn't matter where you place the single cell in the pack, if you put a voltmeter across the terminals it will measure the same voltage.
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