On a large surface, I beleve direct die would be the way to go if there is no other destruction, in a situation like on a peltier is what I would be talking about. A cpu on the other hand has such a high heat density that the heat needs to be spread out a little bit to cool efficiently. The cpu is a peice that can be destroyed because of water soaking into the core or substrate, also, unless you completly bond the block to the cpu, it makes quite the mess to remove.
Jon
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