well, ive got an AOpen case (very similar to yours), except it has a hdd cage above the PSU as well as below the 5 1/4" bays. id try moving your hdds above your PSU. it would be an ideal spot, since theres a spot for an exhaust fan above the PSU (which would draw air over your hdds, cooling them off). then mount the rad and pump at the lower front of your case. if you are using a 7 by 6 inch heatercore, you'll have plenty of room up front.
if you have enough 5 1/4" drive bays open, you could mount your hdds there like you've said befor.
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