you could make a standard ATX case from plexy, then surround the edges with another layer of plexy, but dont extend it past the front or rear. Think of a picture frame arround the front of the tower and the back or the tower, now out of the two frames make a box by connecting them with more plexy. The problem with this, you cant open it to put in hardware from the side. Youwould have to install the mobo and eavrything from the front. This will be a huge pain in the ass since you will have verry verry little room to work with.
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