Those specs are why I said check closely what formulation of the Tygon you use
Notice two things from the R-1000 specs:
Minimum recommended bend radius:
1/2" ID, 1/16" wall thickness -
2-7/8"
1/2" ID, 1/8" wall thickness --
1-3/4"
Also notice the rated working pressures, 10 PSI for the thin wall, 15 PSI for thick wall. (Both above what say a Ehiem 1250 can supply, but for anyone with larger / more powerful pumps, pay attention to those numbers for the Tygon you choose).