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but if you already have a powerful pump to counter the decrease in flow rate..................................
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Then you don't need to run parallel since you have enough head to push through a series setup
jokes aside, I can see suituations where parallel would give better results than series, say you have a 1/2'' cpu block and want to add a gpu block, for whatever reason you can only get a 3/8 or even a 1/4'' block for that. Surely it would be better to *steal* 20% or so of the flowrate from the cpu block(running both in parallel) than to run them in series and reduce the entire system flow to 20-30% of what it was.