Ya... it's as easy as pie.... get a nice little reservoir with a fairly beefy pump, a couple of T or Y connectors, absolutely have to use 1/2" id tubes for the infrastructure. I would recommend medium flow high velocity blocks though...
connect all the pc's up with the blocks in parallel.
you will have to run a Heater core, properly ventilated.

in this picture you can see the core and the open reservoir with the 210GPH Beckit. note the temperature of the liquid, even with 4 overclocked DURONS and a chipset in the loop.
here is some pictures of two of the nodes, the other pc is my
Dualy.