Look at this radiator (BM Opel Corsa). The 2 rooms (inlet and outlet) are asymmetric. I think it's about the loss of load (pressure drop) in the radiator, water comes in the small inlet (right on the pic) to go to the big outlet (Passage of a small section to one bigger (more tubes) so less loss of load )
Someone could confirm or not this explanation? Has someone realized some flow tests in the two differents directions (small-->big and big-->small) to have a comparison?