Are you asking if the water ABOVE the air tap will force it's way into the airtap & force the air back out into the system?
For most SEALED ones, no. As long as the air pocket sits above any inlet or outlet ports you should be good.
If you fill your sink with water, then submerge a shotglass UPISDEDOWN the whole time, it will be under all the water, yet still have the air trapped inside.
If thats not what you're asking, then I misunderstood the question