As for overall flowrate, a number of engineers have posted up various graph work to show the benefits of added flow to conduction. A system balance is still needed, a bad example would be a powerful pump with 1/4" restrictions throughout the loop. Too much heat generated by the larger pump and the system chokes it off. Now having high flowrate and pressure of say 5gpm which accelerates in the block alone will give the possibillity of the benefit of fluid velocity even though flow is restricted to a smaller degree.
I am still testing on my block with possible ways to run it. I do not have the equipment to give highly accurate results but if a benefit in one way over another is repeatable by me then I will move in that direction. My latest test (if you followed the design in my other thread) will be to choke off the upper layer of holes in the block. This will undoubtedly reduce overall flow but at the same time increase velocity in the remaining passageways. Will a benefit be readable by me? I don't know yet so the fun continues.