You can use the
Kryotherm software downloadable here to calculate the information you want depending on your system setup.
Because TEC's operate much more efficiently at voltages well below Vmax, You may get much better cooling with two 172 Watt TEC's at 12V than a single 226 Watt TEC at 12V. It is very dependent on your setup though.
If the setup is going to be CPU-Coldplate-TEC(s)-Waterblock, then the added distance the heat needs to travel in the coldplate, to reach the TEC's, may offset any efficiency gain.