For those x10 remotes... Don't let any X10 software even touch your computer (its all crap)... instead check out the following:
http://max10.sourceforge.net/
Basically you can map any button on the remote (in any of its 4-5 modes) to any clickable item in windows. In addition you can start program, change volume etc etc... So even programs that dont have explicit remote support (eg: winamp) can be controlled from the remote... heck you could even map word's spellcheck to a button if you were so inclined
I've been using the max10 software (with my mouseremote) for 3 years now... Pretty Good stuff... I believe their latest version(s) add support for new types of remotes as well...
Cheers