OK, I'll try and summarise some of the common principles which might apply to your design.
1. Thin base - very little material between the water and the cpu. However, this increases the "spreading resistance" of the base, which leads to point 2.
2. Efficient design - provided you have an efficient design, ie microfins or loads of small pins, then the fact that the heat won't be spreading across the base doesn't matter.
3. Only have fins/pins where you need them - if your design is sufficiently good, then you only need your fin/pin pattern above the core, with a little overlap. (So looking at your first design, the pins in the centre will do almost all of the cooling while the fins leading to the "basins" will simply add flow resistance.
4. Centre Inlet - while not necessary, this has proven to be successful, particularly when combined with jet impingement and microfins/pins. The main benefit is the increased turbulence (GOOD!) which breaks down the barrier layer at the surface, increasing the efficiency of the block.
Follow these simple suggestions with your own interpretation and you shouldn't go too far wrong.
Also, please understand that these are, by no means, rules set in stone that you MUST follow, they are just ideas that people have had a lot of success with recently.
I hope this helps you along your way.
8-ball
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For those who believe that water needs to travel slowly through the radiator for optimum performance, read the following thread.
READ ALL OF THIS!!!!
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