You are discounting the entire pesticide industry, who have seen firsthand how difficult that accelerating natural selection can make their lives. Genes which previously had no use end up saving a few insects because they impart insecticide resistance. The next year, the majority of insects are resistnat because only the remaining bugs could breed and reproduce. There have also been documented cases of moths in europe that were white before smog began to turn the trunks of the trees where they lived grey. Once this happened then birds could see those moths clearly. It wasn't long until most of the moths were not white but grey; again natural selection at work.
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