Putting two dissimilar metals in physical contact makes it likely for corrosion to occur at the boundary between them, which is quite bad. Of course, concentration cells can form along seams of a single metal, so it's generally best to design blocks with rubber seals and nylon screws, though it's difficult to say how much benefit can be seen over the relatively short lifetime of a waterblock.
The voltage potential between copper and aluminum is not altered by reducing the resistance of the electrical contact between them, which is what "shorting" them does.
However, the current between them can certainly be increased by wiring them together. I=V/R. More current means more electrons moving, which means more oxidation.
Of course, there's such a low concentration of metal ions in the cooling fluid that it's possible it won't make a bit of difference.
Alchemy
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