the pin-grid, and in particular the one with pins shaped like what we have here, wants to have flow going through them. Having the inlet right on top of the core, creates what I call (for lack of any other explanation) "the eye of the Storm" effect.
some of us here have tried the 3 inlet derivative already, they might want to give some feedback..

I can imagine the gains/losses to be so minute, bordering on frustration when atempting to quantify.
The primary reason I use copper tops, and with grids in the top plate too, is to aid in obtaining the ideal VDFC configuration. it is not really there to help with cooling directly, although it might very well be the case, when big-ass TECs are being brutalized and tortured