Horizontal or vertical or whatever for your pipe runs makes no difference. Running water through an obstruction (like a water block) results in a head loss (pressure drop) across the obstruction. I'm predicting based on some of BillA's pressure/flow data that with only 6 m of head to work with, you won't push more than 50 l/min through even an unrestrictive block.
More details on pump would be good. A link to it's specifications would be better. An actual P-Q curve would be best.
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